JDRavnos has posted initial thoughts on Vampire: The Masquerade - Bloodlines here, with some interesting new details...

You can breach the Masquerade up to five times, but doing so brings consequences.

"You can switch between 3rd and 1st person, but it defaults to 1st most of the time and during fights involving guns, and 3rd to melee fights."

"The original music helps support the atmosphere, and there is some licensed music from bands who fit well into the gothic punk World of Darkness (Lacuna Coil and Darling Violetta stand out in my mind)."

"The clans weakness are approximated, and they're give benefits as well. During character creation you seem to be limited to the clan's niche as to how you can design your character, but once your in the game the experience points can be spent however you want so if you want a Ventrue brawler or Gangrel seductress you can make one, they just won't be able to do it off the bat."